CAR-T cell therapy holds enormous potential for the treatment of cancer as well as autoimmune and rare diseases. The isolation of T cells from apheresis material collected from a patient is a critically important step in the CAR-T cell manufacturing process.
Explore the use of Gibco™ CTS™ Dynabeads magnetic beads in isolating T cells with high purity and high yield.
Examine the application note from Thermo Fisher Scientific to discover:
-
Methods for isolating and harvesting T cells for downstream applications
-
The use of CTS Detachable Dynabeads for one-step “beads-on-beads” isolation
-
Creation of a single use system prototype to close the supply chain gap
Sequential and direct T cell isolation using CTS Detachable Dynabeads
Flow cytometry results illustrating isolation performance
Benefits and applications of T cell isolation using CTS Detachable Dynabeads CD4 and CD8 beads
Applications and advantages of CTS Detachable Dynabeads CD3/CD28 beads in T cell isolation