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Automated workflow for mRNA In Vitro Transcription (IVT)

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In vitro transcription (IVT) is the gold standard method for large scale production of mRNA drug substances.

Explore a complete automated workflow for IVT, from high-throughput mini-prep scale plasmid purification, to plasmid template linearization, to RNA synthesis and purification.

Learn more now about streamlining early discovery with this inside look at:

  • The varying types of analytical assays: Characterization, In-Process, Release
  • An automated workflow for IVT of mRNA
  • Automated plasmid purification and quality control
  • Plasmid-directed IVT of RNA on magnetic beads (solid-phase IVT)
  • Quality control of purified RNA by direct sequencing and quantification by PCR

Download the IVT application note